Effects of adjunctive daily phototherapy on chronic periodontitis: a randomized single-blind controlled trial
정겨운, 김진우, 김선종, 방은경,
소속 상세정보
정겨운 ( Jung Gyu-Un ) - Ewha Womans University Mokdong Hospital Department of Periodontology
김진우 ( Kim Jin-Woo ) - Ewha Womans University Medical Center Department of Oral and Maxillofacial Surgery
김선종 ( Kim Sun-Jong ) - Ewha Womans University Medical Center Department of Oral and Maxillofacial Surgery
방은경 ( Pang Eun-Kyoung ) - Ewha Womans University Graduate School of Medicine Department of Periodontology
KMID : 0363020140440060280
Abstract
Purpose: The purpose of this randomized single-blind controlled trial was to elucidate the clinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling and root planing (SRP) in patients with chronic periodontitis.
Methods: The study was conducted from December 2013 to May 2014 at Ewha Womans University Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderate chronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio: SRP+PT and SRP (control) groups. All participants underwent full-mouth SRP. PT was performed thrice a day for a month by using electric toothbrushes with embedded light-emitting diodes. Plaque index, gingival index, probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing were assessed before (baseline) and four weeks after (follow-up) the treatment. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Prevotella intermedia, Fusobacterium nucleatum, Parvimonas micra, Campylobacter rectus, Eikenella corrodens, Streptococcus mutans, and Streptococcus sobrinus levels were detected by a real-time polymerase chain reaction at the same points in time.
Results: The clinical parameters improved in both the groups. At the follow-up assessment, PPD was significantly decreased in the SRP+PT group (P=0.00). Further, PPD and CAL showed significantly greater changes in the SRP+PT group than in the SRP group (PPD, P=0.03; CAL, P=0.04). P. gingivalis and T. forsythia levels decreased in this group, but no significant intergroup differences were noted.
Conclusions: Adjunctive PT seems to have clinical benefits, but evidence of its antimicrobial effects is not sufficient. Long-term studies are necessary to develop the most effective PT protocol and compare the effectiveness of PT with and without exogenous photosensitizers.
키워드
Dental scaling ; Periodontal index ; Periodontitis ; Photochemotherapy ; Photosensitizing agents
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